Title:
【発明の名称】14α,17α―エタノ―エストラトリエン
Document Type and Number:
Japanese Patent JPH04502906
Kind Code:
A
Abstract:
PCT No. PCT/DE89/00712 Sec. 371 Date May 13, 1991 Sec. 102(e) Date May 13, 1991 PCT Filed Nov. 10, 1989 PCT Pub. No. WO90/05139 PCT Pub. Date May 17, 1990. (I) (a) (II) (III) New 14 alpha ,17 alpha -ethano-estratrienes of general formula (I) wherein R1 is a hydrogen atom, an alkyl or acyl group with 1 to 12 carbon atoms, R2 is a hydrogen atom or a methyl group, R3 is a hydrogen atom or an acyl group with 1 to 12 carbon atoms and (a) is either (II) or (III), where R4 is an alkyl residue in the alpha or beta position with 1 to 8 carbon atoms or an alpha , beta -alkenyl residue which may contain several double bonds or an alpha , beta -alkinyl residue, both with 2 to 8 carbon atoms, are described. Also described is a process for producing them. These new compounds have a marked oestrogenic activity.
Inventors:
Kirsch, Geralt
Laurent, Henry
Wichelt, Rudolf
Bayer
Elgar, Walter
Bull, James Earl.
Laurent, Henry
Wichelt, Rudolf
Bayer
Elgar, Walter
Bull, James Earl.
Application Number:
JP51154989A
Publication Date:
May 28, 1992
Filing Date:
November 10, 1989
Export Citation:
Assignee:
Schering,Aktiengesellschaft
International Classes:
C07J53/00; A61K31/565; (IPC1-7): A61K31/565; C07J53/00
Attorney, Agent or Firm:
Toshio Yano (2 outside)