Title:
【発明の名称】ウロキナーゼ型プラスミノーゲン活性化因子レセプター
Document Type and Number:
Japanese Patent JPH04506148
Kind Code:
A
Abstract:
The use of substances capable of preventing the binding of a receptor binding form of u-PA to a u-PA receptor (u-PAR) in a mammal and thereby preventing u-PA from converting plasminogen into plasmin thereby preventing cell surface plasminogen activation which is believed to play an important role in tissue remodelling, particularly during cancer invasion for preparing a composition for preventing or counteracting localized proteolytic activity in a mammal, in particular a human.
Inventors:
Dane, Kell
Burasi, Francesco
Roldan, Anne Rowling
Cuberis, Maria Vittoria
Mastí, Maria Theresa
Apella, etre
Schleining, V Day
Beerent, Nils
Rene, Eve
Christensen, peter
Polanen, spear
Salonen, Eva-Maryatta
Stephen, Ross Wei
Tapiovara, Hannere
Vaheri, Antti
Meller, Lisbet Biak
Ellis, Vincent
Run, Leif Leie
Plow, Michael
Pike, charles
Patsy, Laszlo
Burasi, Francesco
Roldan, Anne Rowling
Cuberis, Maria Vittoria
Mastí, Maria Theresa
Apella, etre
Schleining, V Day
Beerent, Nils
Rene, Eve
Christensen, peter
Polanen, spear
Salonen, Eva-Maryatta
Stephen, Ross Wei
Tapiovara, Hannere
Vaheri, Antti
Meller, Lisbet Biak
Ellis, Vincent
Run, Leif Leie
Plow, Michael
Pike, charles
Patsy, Laszlo
Application Number:
JP50630790A
Publication Date:
October 29, 1992
Filing Date:
April 09, 1990
Export Citation:
Assignee:
Cancer Forcesnings Fonden Ahu 1989 (Fonden Chill Fleming Af Experimentel Cancer Forcesning)
International Classes:
A61K38/18; A61K38/49; A61K38/55; A61K39/395; A61K45/00; A61K49/00; A61K51/00; A61P7/04; A61P35/00; C07K1/22; C07K14/00; C07K14/435; C07K14/705; C07K16/00; C07K16/28; C12N5/10; C12N9/72; C12N15/02; A61K38/00; C12N15/09; C12N15/12; C12N15/58; C12P21/02; C12P21/08; C12Q1/68; G01N33/50; G01N33/53; G01N33/566; G01N33/574; G01N33/577; G01N33/86; C12R1/91; (IPC1-7): A61K37/02; A61K39/395; A61K45/00; A61K49/00; A61K49/02; C07K13/00; C07K15/06; C12N5/10; C12N5/20; C12N9/72; C12N15/06; C12N15/12; C12N15/62; C12P21/02; C12P21/08; G01N33/53; G01N33/574; G01N33/577
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)