Title:
【発明の名称】滑膜ホスホリパーゼ
Document Type and Number:
Japanese Patent JPH04506447
Kind Code:
A
Abstract:
Mammalian synovial phospholipase A2 (sPLA2) enzymes are provided, as well as DNA constructs encoding these enzymes, methods of producing the enzymes recombinantly, and antibodies thereto. Therapeutic methods employing anti-synovial phospholipase antibodies are also provided, in addition to diagnostic methods and other applications of sPLA2.
Inventors:
Johnson, Lorin Kay.
Sail Hamer, Jeffrey Jay.
Purzansky, Waldemar
Peter Badass
Sail Hamer, Jeffrey Jay.
Purzansky, Waldemar
Peter Badass
Application Number:
JP50773188A
Publication Date:
November 12, 1992
Filing Date:
August 23, 1988
Export Citation:
Assignee:
Eli Lilly and Company
International Classes:
A61K38/00; A61K39/39; A61K39/395; A61K47/42; A61P29/00; A61P35/00; C07K14/00; C07K16/00; A61K38/46; C07K16/40; C12N9/16; C12N9/18; C12N15/09; C12P21/08; C12Q1/34; G01N33/50; G01N33/531; G01N33/573; (IPC1-7): A61K37/54; A61K39/39; A61K39/395; A61K47/42; C07K13/00; C12N9/16; C12N15/55; C12P21/08
Other References:
J.BIOCHEM=1986
Attorney, Agent or Firm:
Shusaku Yamamoto