Title:
【発明の名称】ピリミジンデオキシリボヌクレオシドの製造用発酵方法
Document Type and Number:
Japanese Patent JPH05504055
Kind Code:
A
Abstract:
DNA coding for at least one enzyme that causes the accumulation of a pyrimidine deoxyribonucleoside is used, in conjunction with metabolic mutations or heterologous DNA coding for metabolic enzymes that also increase pyrimidine deoxyribonucleoside production, to engineer cultured cells to express a pyrimidine deoxyribonucleoside (PdN) in recoverable quantities, providing a commercially useful fermentation source for PdNs.
Inventors:
MacDandris, Russell Theei
Anderson, David M
Anderson, David M
Application Number:
JP50174990A
Publication Date:
July 01, 1993
Filing Date:
December 05, 1990
Export Citation:
Assignee:
Chemjen Corporation
International Classes:
C12N9/00; C12N9/02; C12N9/10; C12N9/12; C12N9/16; C12N15/09; C12P19/38; C12N1/21; C12R1/19; (IPC1-7): C12N1/21; C12N15/52; C12N15/70; C12P19/38
Attorney, Agent or Firm:
Yoshio Kawaguchi