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Title:
【発明の名称】封入すべき外来物質に対する取り込み容量が増加されたリポソームの製造方法
Document Type and Number:
Japanese Patent JPH05504150
Kind Code:
A
Abstract:
PCT No. PCT/EP91/00377 Sec. 371 Date Jun. 22, 1992 Sec. 102(e) Date Jun. 22, 1992 PCT Filed Dec. 9, 1992 PCT Pub. No. WO92/10166 PCT Pub. Date Jun. 25, 1992.Liposome vesicles are prepared containing water or very dilute solutions encapsulated therein. These "empty" liposomes are suspended in a carrier liquid containing, dispersed therein, substances of interest to be loaded into the vesicles and incubated for a period of time at temperatures above the lipids transition temperature, whereby loading by transmembrane permeation occurs in high yields.

Inventors:
Michelle Schneider
Tournier, Elbe
Yasantou, Laurent
Guillo, christian
Lami, Bernard
Application Number:
JP50206292A
Publication Date:
July 01, 1993
Filing Date:
December 09, 1991
Export Citation:
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Assignee:
Blackco International Besloten Fennaught Shap
International Classes:
A61K9/00; A61K9/127; A61K47/48; A61K49/04; B01J13/02; (IPC1-7): B01J13/02; A61K49/04; A61K9/127
Domestic Patent References:
JPH03501251A1991-03-22
Attorney, Agent or Firm:
Takashi Ishida (2 outside)



 
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