【発明の名称】BCH―189および関連化合物の合成のための方法および組成物

Title:

【発明の名称】BCH―189および関連化合物の合成のための方法および組成物

Document Type and Number:

Japanese Patent JPH05505794

Kind Code:

A

Abstract:

The present invention relates to a method of preparing BCH-189 and various analogues of BCH-189 from inexpensive precursors with the option of introducing functionality as needed. This synthetic route allows the stereoselective preparation of the biologically active isomer of these compounds, ²-BCH-189 and related compounds. Furthermore, the stereochemistry at the nucleoside 4'-position can be controlled to produce enantiomerically-enriched ²-BCH-189 and its analogues.

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Inventors:

Riotta, Dennis Sea.
Choi, woo flies

Application Number:

JP50489791A

Publication Date:

August 26, 1993

Filing Date:

January 31, 1991

Export Citation:

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Assignee:

Emory University

International Classes:

A61K31/00; A61K31/39; A61K31/513; A61K31/695; A61K31/7064; A61K31/7068; A61K31/505; A61P31/12; A61P31/18; C07D239/02; C07D327/04; C07D405/04; C07D411/04; C07D451/00; C07F7/18; C07H19/06; C07H19/10; C12P19/38; C12P41/00; A61K; C07D; (IPC1-7): C07D411/04; A61K31/505; A61K31/695; C07D327/04; C07F7/18; C12P41/00

Attorney, Agent or Firm:

Hajime Tsukuni (3 outside)

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