Title:
【発明の名称】RNA療法を提供するためのDNA構造
Document Type and Number:
Japanese Patent JPH06502311
Kind Code:
A
Abstract:
A DNA construct capable of generating a relatively high copy number of therapeutic RNA molecules, including ribozymes and anti-sense RNAs, in target cells for effecting gene therapy. The construct and method of the invention are particularly useful in suppressing hapadnavirus infection and may be clinically effective in treating hepatitis B virus carriers.
Inventors:
Taylor, John Dee
Application Number:
JP50079492A
Publication Date:
March 17, 1994
Filing Date:
October 22, 1991
Export Citation:
Assignee:
FOX CHASE CANCER CENTER
International Classes:
A61K48/00; A61P31/12; C07H21/04; C07K14/02; C07K14/08; C12N15/09; C12N15/113; C12N15/86; C12Q1/68; C12Q1/70; A61K38/00; (IPC1-7): C12N15/11; A61K48/00; C07H21/04
Attorney, Agent or Firm:
Mulberry Hara Fumio