Title:
【発明の名称】髄膜炎菌“Neisseria meningitidis”感染症に対するワクチン
Document Type and Number:
Japanese Patent JPH06503365
Kind Code:
A
Abstract:
PCT No. PCT/FR92/00905 Sec. 371 Date Jun. 2, 1993 Sec. 102(e) Date Jun. 2, 1993 PCT Filed Sep. 29, 1992 PCT Pub. No. WO93/06861 PCT Pub. Date Apr. 15, 1993A vaccinal pharmaceutical composition which comprises, as therapeutic agents, at least a first and a second molecule capable of binding to human transferrin; the said first molecule originating from a first strain of N. meningitidis which possesses a human transferrin receptor in which the lower molecular weight subunit (Tbp2) is recognised by an antiserum to the receptor of N. meningitidis strain 2394 (receptor 2394) and is not recognised by an antiserum to the receptor of N. meningitidis strain 2169 (receptor 2169); and at least a second molecule originating from a second strain of N. meningitidis which possesses a human transferrin receptor in which the lower molecular weight subunit (Tbp2) is recognised by an anti-receptor 2169 antiserum and is not recognised by an anti-receptor 2394 antiserum.
Inventors:
Easy-Millet, Marie-Jose
Application Number:
JP50665393A
Publication Date:
April 14, 1994
Filing Date:
September 29, 1992
Export Citation:
Assignee:
Pasteur Merilleu Serium Eva Saint Society Anonymous
International Classes:
A61P31/04; C07K1/22; C07K14/195; C07K14/22; C07K14/41; A61K39/095; C07K14/705; C12P21/02; A61K38/00; C12R1/36; (IPC1-7): A61K39/095; C07K13/00; C12P21/02
Attorney, Agent or Firm:
Takashi Koshiba