Title:
【発明の名称】抗イディオタイプ抗体を用いる炎症の治療法
Document Type and Number:
Japanese Patent JPH06504426
Kind Code:
A
Abstract:
A method for inhibiting ICAM-1 dependent inflammatory responses by immunizing a patient with anti-ICAM-1 anti-idiotype antibodies or fragments thereof. Anti-ICAM-1 anti-idiotypic antibodies are also disclosed whose antigen combining site binds to an idiotype of an anti-ICAM-1 antibody that inhibits binding of ICAM-1 to an ICAM-1 leukocyte receptor.
Inventors:
Tchaikovsky, Michelle
Kennedy, Charles
Gen Truck Incorporated
Kennedy, Charles
Gen Truck Incorporated
Application Number:
JP51795091A
Publication Date:
May 26, 1994
Filing Date:
October 02, 1991
Export Citation:
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc.
International Classes:
A61K35/12; A61K39/395; A61P29/00; C07K16/28; C07K16/42; C12N15/02; C12P21/08; A61K38/00; (IPC1-7): C12P21/08; A61K35/12; A61K39/395; C12N15/06
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)