Title:
【発明の名称】再発性HSV感染用の免疫療法
Document Type and Number:
Japanese Patent JPH06506705
Kind Code:
A
Abstract:
Immunotherapy for the treatment of Herpes Simplex Virus eye infections is disclosed. The invention involves a local therapeutic or prophylactic vaccine for the eye, comprising one or more recombinant HSV-1 glycoproteins or proteins, specifically gB and gD, in combination with at least one adjuvant to reduce the incidence of primary HSV-1 infection and/or decrease spontaneous HSV-1 ocular shedding which in turn, controls recurrent corneal disease.
Inventors:
Nesburn, Anthony Burt
Wexler, Stephen Lewis
Guyasi, Khomeyon
Wexler, Stephen Lewis
Guyasi, Khomeyon
Application Number:
JP51349993A
Publication Date:
July 28, 1994
Filing Date:
February 03, 1993
Export Citation:
Assignee:
CEDARS-SINAI MEDICAL CENTER
International Classes:
A61K39/245; A61K39/39; A61P27/02; A61P31/12; A61P31/22; C07K14/035; C12N7/01; C12N15/866; A61K39/00; (IPC1-7): A61K39/245
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)