Title:
【発明の名称】気体運搬用及び酸素運搬用脂質小胞
Document Type and Number:
Japanese Patent JPH06507830
Kind Code:
A
Abstract:
The present invention relates to the production of lipid vesicles having a moderately volatile material such as a perfluorocarbon or a silicone oil encapsulated therein. In another aspect, lipid vesicles having a gas-filled center or core are made. The lipid vesicles having gas-filled central core are made by dehydrating vesicles having the moderately volatile liquid encapsulated in the central core. This drives off the water first, allowing the moderately volatile liquid to stabilize the vesicle structure as it dries, finally forming a central void which can refract light. The preferred vesicles of the invention are paucilamellar vesicles.
More Like This:
Inventors:
Henderson, Cheryl Lynn
Wallac, Donald F. H.
Mathur, Rajib
Wallac, Donald F. H.
Mathur, Rajib
Application Number:
JP50783592A
Publication Date:
September 08, 1994
Filing Date:
February 26, 1992
Export Citation:
Assignee:
Micro vesicular systems inc.
International Classes:
A61K8/14; A61K8/70; A61K9/00; A61K9/127; A61K49/22; A61Q19/00; B01J13/02; B01J13/20; C08K9/04; C08L101/00; C11D17/00; (IPC1-7): B01J13/02; A61K9/127; C08K9/04; C08L101/00
Attorney, Agent or Firm:
Motohiro Kurauchi (1 outside)