【発明の名称】新規なガングリオシド誘導体

Title:

【発明の名称】新規なガングリオシド誘導体

Document Type and Number:

Japanese Patent JPH06509350

Kind Code:

A

Abstract:

Novel ganglioside derivatives comprised of a basic natural or semisynthetic ganglioside, in which the carboxyl group in the sialic part of the natural or semisynthetic ganglioside is converted into a carboxylamide with an aliphatic amino acid with a carboxylic or sulfonic acid function, and salts thereof are prepared. The semisynthetic ganglioside components can be chosen from the group consisting of N-acyl-N-lyso-gangliosides, N'-acyl-N'-lyso-gangliosides and N,N'-diacyl-N,N'-di-lyso-gangliosides, wherein "acyl" designates a moiety of an optionally substituted aliphatic acid. The ganglioside derivatives can be used in pharmaceutical preparations to be used in nervous system pathologies.

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Inventors:

Aurelio, Romeo
Gino, Tofano
Alberta, Leon

Application Number:

JP50328193A

Publication Date:

October 20, 1994

Filing Date:

August 01, 1992

Export Citation:

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Assignee:

Fidia Societa Pell Ationi

International Classes:

A61K31/7028; A61K31/715; A61P25/00; A61K31/70; C07H15/10; (IPC1-7): C07H15/10; A61K31/70; A61K37/20

Attorney, Agent or Firm:

Aoyama Ryo (1 person outside)

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