Title:
【発明の名称】新規な3,5-ジ-tert-ブチル-4- ヒドロキシフェニル誘導体、それらの製造方法および薬剤
Document Type and Number:
Japanese Patent JPH06510030
Kind Code:
A
Abstract:
Compounds of the formula I in which A represents a valency, or a straight or a branched alkyl chain having 1 to 5 C atoms, X represents an -NR-CO- (amide) or an -NR-CO-NR- (urea) group, in which R represents a hydrogen atom or a C1-C4-alkyl radical, and Y represents a straight-chain or branched, saturated or unsaturated hydrocarbon chain having 1 to 6 C atoms, which can be substituted by an aryl, hetaryl, aryloxy or arylthio radical, a C3-C6-cycloalkyl radical or an aryl radical, where the aryl or hetaryl radical concerned can each be substituted 1 to 3 times in all possible positions on the ring by CN, hydroxymethyl, methylenedioxy, halogen, trifluoromethyl, C1-C4-alkyl, amino, C1-C4-acylamino, di-(C1-C4)-alkylamino, hydroxyl, C1-C4-alkoxy, carboxyl, ethyl oxyacetate or nitro, with the proviso that Y only denotes unsubstituted phenyl if A has a meaning other than -CH2- or -CH2-CH2-, and their pharmacologically acceptable salts, a process for their preparation and pharmaceutical compositions which contain these compounds, for the treatment of metabolic disorders.
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Inventors:
Dreckman-Berent, Bruno
Heck, Reinhard
Dressel, Alois
Michelle, Helmut
Heck, Reinhard
Dressel, Alois
Michelle, Helmut
Application Number:
JP50407193A
Publication Date:
November 10, 1994
Filing Date:
August 10, 1992
Export Citation:
Assignee:
Boehringer Mannheim Gaem Behr
International Classes:
A61K31/05; A61K31/085; A61K31/09; A61K31/165; A61K31/17; A61K31/34; A61K31/341; A61K31/357; A61K31/36; A61K31/38; A61K31/381; A61K31/40; A61K31/403; A61K31/404; A61K31/415; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/455; A61P3/06; A61P9/10; C07C233/19; C07C233/22; C07C233/25; C07C233/27; C07C233/28; C07C233/29; C07C233/60; C07C233/73; C07C233/75; C07C235/20; C07C235/34; C07C235/78; C07C237/10; C07C237/20; C07C253/30; C07C255/54; C07C255/57; A61K31/035; C07C275/28; C07D207/335; C07D207/337; C07D209/14; C07D209/18; C07D209/26; C07D209/42; C07D213/40; C07D213/56; C07D213/75; C07D213/81; C07D213/82; C07D215/14; C07D233/54; C07D233/64; C07D237/08; C07D237/22; C07D237/24; C07D241/12; C07D241/20; C07D241/24; C07D307/52; C07D307/54; C07D307/68; C07D317/60; C07D317/64; C07D333/20; C07D333/24; C07D333/38; C07D333/70; C07D207/32; (IPC1-7): C07C233/25; C07D333/70; C07D333/24; C07D317/64; C07D307/68; C07D307/54; C07D241/24; C07D241/20; C07D237/24; C07D237/22; C07D233/64; C07D213/82; C07D213/81; C07D213/75; C07D213/56; C07D209/42; C07D207/337; C07C275/28; C07C255/57; C07C253/30; C07C235/34; C07C235/20; C07C233/73; C07C233/60; C07C233/29; C07C233/28; C07C233/27; A61K31/455; A61K31/44; A61K31/415; A61K31/40; A61K31/38; A61K31/36; A61K31/34; A61K31/17; A61K31/165; A61K31/09; A61K31/085; A61K31/05; A61K31/035
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)