Title:
【発明の名称】特定種のLFA-3またはCD2結合蛋白質を投与することによる同種移植または異種移植の寛容性を改善するための方法
Document Type and Number:
Japanese Patent JPH07502495
Kind Code:
A
Abstract:
A protein that binds CD2, which is a derivative of a soluble LFA-3 polypeptide, the derivative being an immunoglobulin fusion comprising the soluble LFA-3 polypeptide fused to an immunoglobulin region, or being the soluble LFA-3 polypeptide linked to a pharmaceutical agent, is used in the preparation of a medicament for use in a method of improving tolerance of transplanted allograft tissue or xenograft tissue in a mammal, including a human, wherein the method comprises implanting in the mammal an allograft or a xenograft and administering the protein.
Inventors:
Wolner, Barbarapee.
Benjamin, Christopher Dee.
Benjamin, Christopher Dee.
Application Number:
JP50724792A
Publication Date:
March 16, 1995
Filing Date:
October 06, 1992
Export Citation:
Assignee:
Byogen incorporated
International Classes:
A61K31/573; A61K38/17; A61K39/395; A61K38/00; A61K45/00; A61P9/00; A61P13/12; A61P37/00; A61P37/06; A61P43/00; C07K14/705; C07K16/28; (IPC1-7): A61K39/395; A61K38/00; A61K39/395
Attorney, Agent or Firm:
Hidekazu Miyoshi (1 outside)