【発明の名称】磁気共鳴造影における持続性フリーラジカルの使用

Japanese Patent JPH07502724

A

PCT No. PCT/EP92/01793 Sec. 371 Date Mar. 18, 1994 Sec. 102(e) Date Mar. 18, 1994 PCT Filed Aug. 6, 1992 PCT Pub. No. WO93/02711 PCT Pub. Date Feb. 18, 1993.The present invention provides the use of a persistent pi -system free radical for the manufacture of a contrast medium for use in magnetic resonance imaging, wherein the electron delocalising pi -system of said radical comprises at least one homo or heterocyclic ring, said radical being other than the chloranil semiquinone anion radical or a trityl radical. Also provided are magnetic resonance imaging contrast media containing and methods using such radicals.

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Goalman, claes
Anderson, Sven
Lycee, Frode
Wistland, Lars-Guerlain
Wixtreme, Harkan

JP50328793A

March 23, 1995

August 06, 1992

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Nicomde Innovation Arb

A61B5/055; A61K49/00; A61K49/20; C07B60/00; C07C43/20; C07C45/67; C07C45/70; C07C46/00; C07C49/747; C07C49/753; C07C50/28; C07C69/92; C07C233/69; C07C235/48; C07C255/32; C07C255/36; C07C255/41; C07C309/66; C07C317/22; C07C317/24; C07C323/20; C07D209/36; C07D209/48; C07D215/24; C07D311/82; C07D339/06; C07D471/04; C07D493/04; C07D495/04; C07D497/04; C07D519/00; A61K; (IPC1-7): A61K49/00; A61B5/055; C07B61/02; C07C43/20; C07C49/747; C07C50/28; C07C69/92; C07C235/48; C07C255/32; C07C309/66; C07C317/24; C07C323/20; C07D209/48; C07D215/24; C07D471/04; C07D493/04; C07D495/04; C07D497/04

Shunichiro Suzuki

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