【発明の名称】血小板及び/又は内皮下層へのvWFの結合の拮抗剤である抗血栓性ポリペプチド

Title:

【発明の名称】血小板及び/又は内皮下層へのvWFの結合の拮抗剤である抗血栓性ポリペプチド

Document Type and Number:

Japanese Patent JPH07503369

Kind Code:

A

Abstract:

Recombinant polypeptides consisting of an adhesive portion derived from the structure of the vWF which is at least partially antagonistic to the bond between said vWF and the platelets and/or the subendothelium, as well as a portion for stabilising and presenting it $i(in vivo); preparation thereof; and pharmaceutical compositions containing said polypeptides.

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Inventors:

Freres, Reinhard
Fournier, Alain
Giton, Jiyan-Dominique
Jiyun, Jealal
Yee, Patrice

Application Number:

JP51298893A

Publication Date:

April 13, 1995

Filing Date:

January 28, 1993

Export Citation:

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Assignee:

Loan-Poulin L'Oré Societe Anonym

International Classes:

C12N15/09; A61K38/43; A61P7/02; C07K14/745; C07K14/755; C07K14/76; C07K14/765; C07K19/00; C12N1/19; C12N1/21; C12N15/12; C12P21/02; A61K38/00; C12R1/19; C12R1/645; (IPC1-7): C12N15/09; A61K38/43; C07K19/00; C12N1/19; C12N1/21; C12P21/02

Attorney, Agent or Firm:

Heiyoshi Odashima

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