Title:
【発明の名称】Mycobacterium tuberculosisにおける抗生物質耐性の迅速検出法
Document Type and Number:
Japanese Patent JPH07506003
Kind Code:
A
Abstract:
Multidrug resistant strains of Mycobacterium tuberculosis represent a considerable threat to public health worldwide. Resistance to isoniazid (INH), rifampicin or analogues thereof, or streptomycin, i.e. key components of anti-tuberculosis regimens, need frequently to be detected. The invention involves the detection of a mutation in either the katG gene (isoniazid resistance), the rpoB gene (rifampicin resistance) or rpsL gene (streptomycin resistance).
Inventors:
Heim, Beate
Cole, Stewart
Young, douglas
Tsang Inn
Onor, Nadin
Terenti, amario
Boardmar, Thomas
Cole, Stewart
Young, douglas
Tsang Inn
Onor, Nadin
Terenti, amario
Boardmar, Thomas
Application Number:
JP51892393A
Publication Date:
July 06, 1995
Filing Date:
April 30, 1993
Export Citation:
Assignee:
INSTITUT PASTEUR
Medical Research Council
Assistance Publick
Universite Pierre et Mari Curie (Paris Sixs)
Université de Bern
Medical Research Council
Assistance Publick
Universite Pierre et Mari Curie (Paris Sixs)
Université de Bern
International Classes:
C12N9/08; C12Q1/18; C12Q1/68; G01N33/15; C12N15/09; G01N33/50; C12R1/32; (IPC1-7): C12N15/09; C12Q1/68
Attorney, Agent or Firm:
Hajime Tsukuni (2 outside)