Title:
【発明の名称】(3-ビニルフエニル)フエニルメタン
Document Type and Number:
Japanese Patent JPH0784397
Kind Code:
B2
Abstract:
The invention relates to a new compound (3-Vinylphenyl)phenylmethane,and a method for producing alpha -(3-benzoylphenyl)propionic acid of ketoprofen without difficulty at low cost and in a high yield. The method comprises the steps of: reacting (3-vinylphenyl)phenylmethane with carbon monoxide and hydrogen, water or lower alcohol in the presence of a transition metal carbonylation catalyst to form alpha -(3-benzylphenyl)propionic acid derivative, and when the thus obtained compound is an aldehyde, oxidizing methylene group and formyl group of the compound simultaneously or sequentially, or when the obtained compound is an acid or its ester, oxidizing the methylene group of the compound, and if necessary performing a hydrolysis step.
Inventors:
Fifty Shimizu
Matsumura Yasuo
Yu Arai
Matsumura Yasuo
Yu Arai
Application Number:
JP6646387A
Publication Date:
September 13, 1995
Filing Date:
March 20, 1987
Export Citation:
Assignee:
Nippon Petrochemical Co., Ltd.
International Classes:
C07C1/00; C07C15/50; C07C45/50; C07C47/23; C07C51/14; C07C51/16; C07C51/215; C07C51/235; C07C51/255; C07C59/84; C07C67/00; (IPC1-7): C07C15/50
Attorney, Agent or Firm:
Maejima Hajime
Next Patent: ペンタフルオロジクロロプロパン類の製造方法