Title:
【発明の名称】VII因子の精製
Document Type and Number:
Japanese Patent JPH08508264
Kind Code:
A
Abstract:
PCT No. PCT/DK94/00122 Sec. 371 Date May 25, 1995 Sec. 102(e) Date May 25, 1995 PCT Filed Mar. 24, 1994 PCT Pub. No. WO94/22905 PCT Pub. Date Oct. 13, 1994The present invention describes a method for controlled activation and degradation of FVII during purification whereby a solution of Factor VII is subjected to a number of chromatographic purification steps wherein Zn++ is present in at least one of the purification steps. The present invention also describes a method for controlled activation and degradation of FVII wherein a solution of FVII is applied to a number of anion exchange and immunoaffinity columns.
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Inventors:
Tony, Jergensen
Pedersen Anders Jellholt
Pedersen Anders Jellholt
Application Number:
JP52155294A
Publication Date:
September 03, 1996
Filing Date:
March 24, 1994
Export Citation:
Assignee:
NOVO NORDISK AS (DK)
International Classes:
A61K35/12; A61K35/16; C07K1/18; C07K1/22; C07K14/745; C12N9/64; A61K38/43; (IPC1-7): C07K14/745; C07K1/18; C07K1/22
Attorney, Agent or Firm:
Takashi Ishida (3 others)