Title:
【発明の名称】皮膚へのエストラジオール放出用活性物質パッチ
Document Type and Number:
Japanese Patent JPH08508266
Kind Code:
A
Abstract:
PCT No. PCT/EP94/00670 Sec. 371 Date Feb. 12, 1996 Sec. 102(e) Date Feb. 12, 1996 PCT Filed Mar. 7, 1994 PCT Pub. No. WO94/22481 PCT Pub. Date Oct. 13, 1994An active substance patch releasing estradiol to the skin is characterized by the fact that it consists essentially of a backing layer and an attached active substance reservoir which comprises pressure sensitive adhesive and in which the active substance is at least partially soluble, and of a removable protective layer covering the adhesive film, the active substance reservoir being a polymer matrix which-in order to improve the bioavailability of the estradiol-comprises an added penetration enhancer of the general formula: wherein R=-CH2OH or -CH2-O-CH2-CHOH-CH2OH.
Inventors:
Murphy, Teresa Maria
Application Number:
JP52158794A
Publication Date:
September 03, 1996
Filing Date:
March 07, 1994
Export Citation:
Assignee:
Ertesue Roman Therapy-Usuteme Gesellschaft Mitt Beschlenktel Haftung und Companion Commandet Gesellschaft
International Classes:
A61K9/70; A61K31/565; A61K47/22; A61P5/00; (IPC1-7): A61K31/565; A61K9/70; A61K47/22
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)