Title:
【発明の名称】インシュリン様成長因子結合タンパク質の使用方法
Document Type and Number:
Japanese Patent JPH08508296
Kind Code:
A
Abstract:
The invention relates to methods of using insulin-like growth factor binding proteins ("IGFBPs"), including IGFBP-1 or modified forms of IGFBP-1 as therapeutic agents. Modified forms include IGFBP-1 attached to a polymer or two IGFBP-1 molecules attached to opposite ends of a polymer. The methods involve administering IGFBPs, including IGFBP-1 or a modified form of IGFBP-1 to a patient having an IGF associated condition sufficient to cause a therapeutic effect. The invention also relates to non-phosphorylated IGFBPs useful in the methods.
Inventors:
Cocks, George N
Russell, Deborah A
Russell, Deborah A
Application Number:
JP52247794A
Publication Date:
September 03, 1996
Filing Date:
April 06, 1994
Export Citation:
Assignee:
Am Jien Bruder Incorporated
International Classes:
C12N15/09; A61K38/27; A61P3/08; A61P3/10; A61P35/00; C07K14/46; C07K14/47; C12N1/21; C12N15/12; C12P21/02; A61K38/00; C12R1/19; (IPC1-7): A61K38/27; A61K38/27; C07K14/46; C12P21/02
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)