Title:
【発明の名称】ロイコトリエン生合成阻害剤としてのフロ[3,2-b]ピリジンおよびチエノ[3,2-b]ピリジン
Document Type and Number:
Japanese Patent JPH08510723
Kind Code:
A
Abstract:
Compounds having the formula I: I are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomemlar nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
Inventors:
Reggie, Sergey
Hatsuchinson, Jiyoung H
Hatsuchinson, Jiyoung H
Application Number:
JP52148294A
Publication Date:
November 12, 1996
Filing Date:
March 10, 1994
Export Citation:
Assignee:
Merck Frost Canada Inc.
International Classes:
A61K31/44; A61K45/06; A61P43/00; C07D491/04; C07D491/048; C07D495/04; C07D513/04; (IPC1-7): C07D491/048; A61K31/44; A61K45/06; C07D495/04; C07D513/04
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)