Title:
【発明の名称】サイクロスポリン-含有粉末組成物
Document Type and Number:
Japanese Patent JPH09501701
Kind Code:
A
Abstract:
The present invention relates to a cyclosporin-containing powder composition which comprises cyclosporin, a non-ionic hydrophilic surfactant and a porous carrier. In addition, the present invention relates to a method for preparing the cyclosporin-containing powder composition which comprises dissolving cyclosporin and a non-ionic hydrophilic surfactant in an organic solvent, adding a porous carrier to the resulting solution and then evaporating the organic solvent from the mixture. The powder composition of the present invention is stable and does not require a special manufacturing technique when it is formulated. In addition, since the powder composition of the present invention does not contain an organic solvent, the necessity of a special package is excluded. Furthermore, the composition of the present invention provides an improved bioavailability which results in decrease of a single dosage, and therefore, can contribute to the alleviation of the side effects associated with cyclosporin.
Inventors:
Kim Jung Woo
Shin Hee Jung
Bak Jun Kyu
Min Kyung Bok
Shin Hee Jung
Bak Jun Kyu
Min Kyung Bok
Application Number:
JP52226994A
Publication Date:
February 18, 1997
Filing Date:
September 16, 1994
Export Citation:
Assignee:
Jung Gun Dan Corporation
International Classes:
A61K9/14; A61K9/16; A61K9/48; A61K38/00; A61K38/13; A61K47/02; A61K47/04; (IPC1-7): A61K38/00; A61K9/14; A61K47/02
Attorney, Agent or Firm:
Ueki Kuichi