Title:
【発明の名称】骨形態形成蛋白変異体
Document Type and Number:
Japanese Patent JPH09506259
Kind Code:
A
Abstract:
DNA molecules encoding mutant forms of bone morphogenetic proteins (BMP) are disclosed, The mutant forms of BMP can be produced bacterially and refolded to produce biologically active homodimers or heterodimers of BMP. A method of making such mutant BMPs is also disclosed.
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Inventors:
Wolfman, Neil Em
John McCoy
John McCoy
Application Number:
JP51619695A
Publication Date:
June 24, 1997
Filing Date:
November 15, 1994
Export Citation:
Assignee:
Genetics Institute, Inc.
International Classes:
C07K14/51; C12N15/12; C12P21/02; C12N15/09; C12R1/19; (IPC1-7): C12N15/09; C07K14/51; C12P21/02
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)