Title:
【発明の名称】供血者血液特性の制御
Document Type and Number:
Japanese Patent JPH09509681
Kind Code:
A
Abstract:
A new citrate-based anticoagulant for donor whole blood provides good platelet yield and cell morphology at a significantly reduced risk of donor paresthesia during apheresis procedures. The primary citrate anticoagulant compositions include a citric acid to total citrate ratio greater than about 30%. The anticoagulants are mixed with whole blood to provide an anticoagulated blood mixture which contains a citric acid concentration of greater than about 5.0 mM, a total citrate concentration of less than about 20 mM, and an initial blood pH of less than about 6.75. The platelet rich products including PRP and PC prepared from blood collected in accordance with the invention exhibit better platelet yields and better platelet morphology on storage.
Inventors:
Graud, gerald, a
Stewart, mary, a
Stewart, mary, a
Application Number:
JP51873496A
Publication Date:
September 30, 1997
Filing Date:
August 22, 1995
Export Citation:
Assignee:
Baxter, International, Inc.
International Classes:
A61B5/15; A61K35/14; (IPC1-7): A61K35/14; A61B5/14
Attorney, Agent or Firm:
Michio Akaoka (1 person outside)