Title:
【発明の名称】発色団に直接的にまたは非直接的に連結した、ミカエル-アクセプター、特にマレイミドまたはマレイン酸誘導体を含む化合物および長期間継続する日焼け止め組成物におけるこれらの使用
Document Type and Number:
Japanese Patent JPH10502338
Kind Code:
A
Abstract:
The present invention relates to compounds which are useful as sunscreens. The compounds persist on the skin for much longer than conventional sunscreens because they comprise a Michael acceptor linked directly or indirectly to a chromophore. The Michael acceptor is capable of undergoing a conjugate addition reaction with thiol groups present in cysteine residues of keratin and thus the compound is chemically bound to the skin and will not be removed by immersion in water.
Inventors:
Davison, Bruce, Everett
Johns, Bryan, Colin, Nicholas, Morgan
Gunnerin, Sharon, Robin
Bishop, Paul, Beaumont
Jack, david
Johns, Bryan, Colin, Nicholas, Morgan
Gunnerin, Sharon, Robin
Bishop, Paul, Beaumont
Jack, david
Application Number:
JP52878495A
Publication Date:
March 03, 1998
Filing Date:
May 09, 1995
Export Citation:
Assignee:
Vanguard Medica Limited
International Classes:
A61K8/00; A61K8/36; A61K8/41; A61K8/42; A61K8/44; A61K8/49; A61K31/40; A61Q17/04; C07C50/02; C07C50/28; C07C50/38; C07C69/60; C07C225/28; C07C229/44; C07C231/02; C07C233/20; C07C233/27; C07C233/32; C07C233/33; C07C233/55; C07D207/452; C09K3/00; C07D207/44; (IPC1-7): C07C50/02; A61K7/42; C07C50/28; C07C50/38; C07C69/60; C07C225/28; C07C229/44; C07C231/02; C07C233/20; C07D207/452; C09K3/00
Attorney, Agent or Firm:
Mikio Hatta (1 outside)