Title:
【発明の名称】抗ヘリコバクター剤である、アゾロンのスルホンアミド誘導体
Document Type and Number:
Japanese Patent JPH10502386
Kind Code:
A
Abstract:
The invention is concerned with the compounds having the formula (I) the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Y is CH or N; R1, R2 and R3 each independently are hydrogen or C1-4alkyl; R4 and R5 each independently are hydrogen, halo, C1-4alkyl, C1-4alkyloxy, hydroxy, trifluoromethyl, trifluoromethyloxy or difluoromethyloxy; R6 is C1-4alkyl; or phenyl optionally substituted with halo, C1-4alkylcarbonylamino, C1-4alkyloxy, C1-4alkyl or nitro; Z is C=O or CHOH; and is a radical of formula (a-1) (a-2) (a-3) (a-4) (a-5) (a-6) or (a-7) Compositions comprising said compounds, processes for preparing the same and the use of these compounds as a method of treating Helicobacter infection.
Inventors:
Jerez, Jiang
Stoke Brex, Raymond Antoine
Mostman, Joseph Hector
Van der Beken, Louis Joseph Joseph Elisabeth
Stoke Brex, Raymond Antoine
Mostman, Joseph Hector
Van der Beken, Louis Joseph Joseph Elisabeth
Application Number:
JP50411295A
Publication Date:
March 03, 1998
Filing Date:
July 05, 1995
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
A61K31/41; A61K31/415; A61K31/44; A61K31/495; A61K31/50; A61K31/505; A61P1/00; A61P1/04; A61P31/04; C07D233/70; C07D249/12; C07D401/04; (IPC1-7): C07D249/12; A61K31/415; A61K31/495; A61K31/50; A61K31/505; C07D233/70; C07D401/04
Attorney, Agent or Firm:
Heiyoshi Odashima