Title:
【発明の名称】薬用エーロゾルを含むヒドロフルオロカーボン推進剤
Document Type and Number:
Japanese Patent JPH10502906
Kind Code:
A
Abstract:
1,1,1,2,3,3,3-heptafluoropropane (HFC-227) has been identified as a highly polar propellant. Surfactants which have an elevated value (9.6 or greater) for their hydrophilic-lipophilic balance (HLB) can be used as suspending, wetting, and lubricating agents or cosolvents in metered dose inhaler (MDI) formulations pressurized with HFC-227 or propellant blends that contain HFC-227. Particularly preferred surfactants include polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan mono-oleate, polyethylene glycol 300, propoxylated polyethylene glycol, polyoxyethylene 4 lauryl ether, and diethylene glycol monoethyl ether.
Inventors:
Byron, Peter
Frank, Brondino
Frank, Brondino
Application Number:
JP52652895A
Publication Date:
March 17, 1998
Filing Date:
April 11, 1995
Export Citation:
Assignee:
The Center for Innovative Technology
International Classes:
A61K9/00; A61K9/12; (IPC1-7): A61K9/12
Attorney, Agent or Firm:
Uchihara Shin