Title:
【発明の名称】インフルエンザウィルスの調製方法と、それによって得られる抗原と、抗原の利用
Document Type and Number:
Japanese Patent JPH10504033
Kind Code:
A
Abstract:
PCT No. PCT/FR95/00727 Sec. 371 Date May 27, 1997 Sec. 102(e) Date May 27, 1997 PCT Filed Jun. 6, 1995 PCT Pub. No. WO96/05294 PCT Pub. Date Feb. 22, 1996Method for preparing purified influenza antigens from a fluid containing influenza virus, comprising the steps of concentration, purification, fragmentation and, where appropriate, inactivation, characterized in that: A. either the purification step entails several ultracentrifugation steps separated by a filtration step, B. or the fragmentation step is performed on the live virus in the presence of an amphiphilic nonionic detergent, followed by a removal of undesirable substances by filtration, retaining all of the viral constituents, or these two steps are carried out in any order.
Inventors:
Violey, Jean-Michel
Cool, gui
Gerdille, Catherine
Charmeau, Herve
McVerry, Patrick
Cool, gui
Gerdille, Catherine
Charmeau, Herve
McVerry, Patrick
Application Number:
JP50705396A
Publication Date:
April 14, 1998
Filing Date:
June 06, 1995
Export Citation:
Assignee:
Pasteur Mérieille Serium Eva Saint
International Classes:
C12N7/00; A61K39/145; A61K49/00; A61P31/16; C12N7/06; (IPC1-7): A61K39/145; A61K49/00; C12N7/00
Attorney, Agent or Firm:
Takashi Koshiba (1 person outside)