Title:
【発明の名称】ワクチン組成物
Document Type and Number:
Japanese Patent JPH10506405
Kind Code:
A
Abstract:
PCT No. PCT/GB95/02231 Sec. 371 Date Apr. 2, 1997 Sec. 102(e) Date Apr. 2, 1997 PCT Filed Sep. 21, 1995 PCT Pub. No. WO96/10421 PCT Pub. Date Apr. 11, 1996The invention relates to a vaccine composition adapted for mucosal administration, and in particular for intranasal administration, the composition comprising an influenza virus antigen or antigens, such as haemagglutinin and neuraminidase influenza virus antigens, and an effective adjuvant amount of a chitosan. The compositions can be used to immunise a host against infection with influenza, the chitosan serving to enhance the stimulation of a protective IgA mucosal immune response and an IgG systemic immune response.
Inventors:
Chatfield, Stephen, Neville
Application Number:
JP51148896A
Publication Date:
June 23, 1998
Filing Date:
September 21, 1995
Export Citation:
Assignee:
Medeva Holdings B.V.
International Classes:
A61K9/12; A61K38/36; A61K39/145; A61K39/39; A61K47/36; A61P31/16; C07K16/10; (IPC1-7): A61K39/145; A61K9/12; A61K38/36; A61K39/39; A61K47/36
Attorney, Agent or Firm:
Yasuo Ishikawa