Title:
【発明の名称】新規受容体
Document Type and Number:
Japanese Patent JPH10511083
Kind Code:
A
Abstract:
PCT No. PCT/EP95/04998 Sec. 371 Date Sep. 26, 1997 Sec. 102(e) Date Sep. 26, 1997 PCT Filed Dec. 11, 1995 PCT Pub. No. WO96/18650 PCT Pub. Date Jun. 20, 1996A method for identifying anti-convulsant compounds is presented. The binding of test compounds with a receptor obtained from rat forebrain is determined. The receptor has a Kd of about 40 nM and a molecular weight of about 130 kD. Two pyran compounds that bind to the receptor are also disclosed.
Inventors:
Hurden, Hugh Jonathan
Jeffrey Clifford, German
Chan, Wai Nugo
Jeffrey Clifford, German
Chan, Wai Nugo
Application Number:
JP51828395A
Publication Date:
October 27, 1998
Filing Date:
December 11, 1995
Export Citation:
Assignee:
SmithKline Beecham Public Limited Company
International Classes:
G01N33/53; A61K38/00; A61K39/395; A61P9/10; A61P25/00; A61P25/28; A61P25/30; A61P43/00; C07B59/00; C07D311/68; C07D405/12; C07K14/705; C07K16/28; C12P21/08; C12Q1/02; G01N33/577; (IPC1-7): C07K14/705; A61K38/00; A61K39/395; C07D311/68; C07D405/12; C07K16/28; C12P21/08; C12Q1/02; G01N33/53; G01N33/577
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)