Title:
【発明の名称】安定な脂質含有薬剤送達複合体及びこれらの製造方法
Document Type and Number:
Japanese Patent JPH10512882
Kind Code:
A
Abstract:
Novel stable, concentrated, biologically active and ready-to-use lipid-comprising drug delivery complexes and methods for their production are described. The biological activity of the complexes produced are comparable to the formulations prepared according to the prior art admixture method and upon purification, the complexes produced by the method of this invention are 50 to 500 fold more concentrated than the complexes formed by admixture. The method described herein provides for the large scale production of lipid-comprising drug delivery systems useful for gene therapy and other applications.
Inventors:
Khao, Xian
Fang, leaf
Fang, leaf
Application Number:
JP52295496A
Publication Date:
December 08, 1998
Filing Date:
January 23, 1996
Export Citation:
Assignee:
University of Pittsburgh
International Classes:
A61K9/127; A61K48/00; C12N15/88; (IPC1-7): A61K9/127; A61K48/00
Attorney, Agent or Firm:
Hajime Tsukuni (3 outside)