Title:
【発明の名称】(5-カルボキサミドまたは5-フルオロ)-(2’,3’-不飽和または3’-改変)ピリミジンヌクレオシド
Document Type and Number:
Japanese Patent JPH10512887
Kind Code:
A
Abstract:
A method and composition for the treatment of HIV and HBV infections in humans and other host animals is disclosed that includes the administration of an effective amount of a Ä5-carboxamido or 5-fluoroÜ-2',3'-dideoxy-2',3'-didehydro-pyrimidine nucleoside or a Ä5-carboxamido or 5-fluoroÜ-3'-modified-pyrimidine nucleoside, mixtures thereof, or a pharmaceutically acceptable derivative or derivatives thereof, including an N-1 or N-4 alkylated or acylated derivative, or a pharmaceutically acceptable salt thereof, in a pharmaceutically acceptable carrier.
Inventors:
Synergy, Raymond F
Liotta, Dennis Sea
Liotta, Dennis Sea
Application Number:
JP52299096A
Publication Date:
December 08, 1998
Filing Date:
January 29, 1996
Export Citation:
Assignee:
Emory University
International Classes:
C07D239/34; A61K9/20; A61K31/505; A61K31/513; A61K31/522; A61K31/675; A61K31/70; A61K31/7042; A61K31/7052; A61K31/7064; A61K31/7068; A61K31/7072; A61K38/21; A61K45/06; A61P31/12; A61P31/18; A61P31/20; A61P37/04; C07D239/38; C07D405/04; C07H19/06; (IPC1-7): C07D239/34; A61K31/505; A61K31/70; C07D239/38; C07H19/06
Domestic Patent References:
| JPH02152976A | 1990-06-12 | |||
| JPH05345775A | 1993-12-27 | |||
| JPH03148292A | 1991-06-25 | |||
| JPH0245486A | 1990-02-15 | |||
| JPH04253989A | 1992-09-09 |
Foreign References:
| NL8901258A | 1990-12-17 | |||
| WO1994027616A1 | 1994-12-08 |
Attorney, Agent or Firm:
Hajime Tsukuni (3 outside)