Title:
【発明の名称】21―(2―オキソテトラヒドロフラン)チオプレグナン誘導体、それらの製造方法、およびそれらを含有した医薬組成物
Document Type and Number:
Japanese Patent JPH11501676
Kind Code:
A
Abstract:
PCT No. PCT/GB96/03153 Sec. 371 Date Jun. 24, 1998 Sec. 102(e) Date Jun. 24, 1998 PCT Filed Dec. 19, 1996 PCT Pub. No. WO97/24367 PCT Pub. Date Jul. 10, 1997Compounds of the pregnane series are described having general formula (I) or their solvates in which R1 individually represents -OC(=O)C1-6 alkyl; R2 individually represents hydrogen, methyl (which may be in the alpha or beta configuration) or methylene; or R1 and R2 together represent formula (a) where R5 and R6 are the same or different and each represents hydrogen or C1-6 alkyl; R3 and R4 are the same or different and each represents hydrogen or halogen; and +Z represents a single or a double bond. Compounds of formula (I) and their solvates are useful as anti-inflammatory or anti-allergic agents.
Inventors:
Keith, Bigga Dyke
Rosanna, Mary, Farrell
Rosanna, Mary, Farrell
Application Number:
JP52409697A
Publication Date:
February 09, 1999
Filing Date:
December 19, 1996
Export Citation:
Assignee:
GLAXO GROUP LTD.
International Classes:
A61K31/00; A61P29/00; C07J31/00; A61K31/565; C07J71/00; (IPC1-7): C07J31/00; A61K31/565; C07J71/00
Attorney, Agent or Firm:
Kazuo Sato (2 outside)