Title:
【発明の名称】グルカゴン様インシュリン分泌性ペプチドの経頬送達
Document Type and Number:
Japanese Patent JPH11513982
Kind Code:
A
Abstract:
Drug delivery systems and methods for administering a glucagon-like insulinotropic peptide to the buccal mucosa for transmucosal drug delivery are described. The drug delivery systems comprise a drug composition containing an effective amount of the glucagon-like insulinotropic peptide and an effective amount of a permeation enhancer for enhancing permeation of glucagon-like insulinotropic peptide through the buccal mucosa and means for maintaining the drug composition in a drug transferring relationship with with buccal mucosa. These systems can be in free form, such as creams, gels, and ointments, or can comprise a device of determined physical form, such as tablets, patches, and troches. A preferred glucagon-like insulinotropic peptide is GLP-1(7-36)amide.
Inventors:
Haver, Sonia Jay
Charles Dee, Evert
Gutniak, Mark Kay
Charles Dee, Evert
Gutniak, Mark Kay
Application Number:
JP51671297A
Publication Date:
November 30, 1999
Filing Date:
October 22, 1996
Export Citation:
Assignee:
Ceratech Incorporated
International Classes:
A61K9/70; A61K9/00; A61K38/04; A61K38/26; A61L15/00; (IPC1-7): A61K38/04; A61K9/70; A61L15/00
Attorney, Agent or Firm:
Kazuo Shamoto (4 outside)