Document Type and Number:
Japanese Patent JPS4856695
Kind Code:
A
Abstract:
Novel 6-APA, 7-ACA, and 7-ADCA derivatives are described which comprise phosphorylated derivatives of 6-APA, 7-ACA, or 7-ADCA and the corresponding acylated derivatives thereof. The novel compounds are prepared by the reaction of 6-APA, 7-ACA, 7-ADCA or a salt thereof with a phosphorus halide in the presence of an acid acceptor and subsequently acylating the thus formed phosphorylated compound, to form a phosphorylated acylated derivative which upon hydrolysis with water splits off the protective group(s) to provide the corresponding semi-synthetic penicillin or cephalosporin having useful antibacterial activity.
Application Number:
JP11196872A
Publication Date:
August 09, 1973
Filing Date:
November 08, 1972
Export Citation:
International Classes:
C07D499/08; C07D499/04; C07D499/10; C07D499/12; C07D499/21; C07D501/06; C07F9/6561; (IPC1-7): C07D99/14
Domestic Patent References:
| JPS4738991A | ||||
| JPS4738990A |