Document Type and Number:
Japanese Patent JPS4930380
Kind Code:
A
Abstract:
1380682 2-Aminoisoquinoline derivatives GRUPPO LEPETIT SpA 7 Sept 1972 [12 June 1972] 41593/72 Heading C2C The invention comprises compounds of formula wherein one of X, Y is O and the other is H 2 ; R is H, up to C 8 alkyl or alkynyl, up to C 8 alkenyl (possibly substituted by Ph, which may be substituted), cycloalkenyl, C 1-8 alkylsulphonyl or PhSO 2 ; and R 1 is up to C 8 alkenyl (possibly substituted as above) or alkynyl, or cycloalkenyl, or RR 1 N is* optionally substituted Phup to C 8 -alkenylideneamino. These compounds are prepared by (a) reacting a corresponding compound where R 1 is H, with R 1 - halide, (b) hydrolysing a compound where R is C 1-8 alkylsulphonyl or PhSO 2 , to obtain the compounds where R is H, or (c) in case *, reacting a compound where R = R 1 = H with an appropriate arylalkenal. Therapeutic compositions for oral, parenteral or rectal administration comprise compounds of the above formula, which have antiinflammatory activity.
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Application Number:
JP11133972A
Publication Date:
March 18, 1974
Filing Date:
November 08, 1972
Export Citation:
International Classes:
C07D217/08; C07D217/24; (IPC1-7): C07D35/10