Document Type and Number:
Japanese Patent JPS5071786
Kind Code:
A
Abstract:
1482921 Polymers containing diazomethylene groups GLAXO LABORATORIES Ltd 30 July 1974 [31 July 1973] 36384/73 Headings C3P and C3R The invention comprises polymers containing a plurality of diazomethylene groups, which are prepared by oxidation of corresponding polymers containing hydrazone groups, e.g. with peracetic acid or chloramine T. The following reaction sequences are given in specific examples: (A) styrene/divinyl benzene copolymer, polystyrene, isotactic polystyrene and macroreticular styrene/divinyl benzene copolymer are each reacted with benzoyl chloride, then the resulting benzoyl groups reacted with hydrazine, and the resulting hydrazone groups are oxidized to diazomethylene groups; (B) styrene/divinyl benzene copolymer is subjected to a similar sequence as in (A) except that in the first step alkoxysubstituted benzoyl chlorides are used; (C) styrene/divinyl benzene copolymer is reacted with diphenylcarbamoyl chloride to give groups, which are hydrolysed to -COOH groups, which are reacted with thionyl chloride to give -COCl groups, which are reacted with benzene to give -COPh groups, which are then reacted with hydrazine and oxidized; (D) styrene/divinyl benzene copolymer containing formyl substituents is reacted with hydrazine and then oxidized; (E) styrene/ divinyl benzene/methyl vinyl ketone copolymer is reacted with hydrazine and oxidized; (F) methacrylic acid/divinyl benzene copolymer is reacted with thionyl chloride, the -COCl groups then reacted with toluene, and the keto groups then reacted with hydrazine and oxidized; and (G) benzyl chloride is polymerized in the presence of SnCl 4 to give poly(benzyl), i.e. -(CH 2 -phenylene-) n -, which is oxidized with nitric acid to give poly(benzoyl), i.e. the methylene groups in the chain are converted to keto groups, which are then reacted with hydrazine, followed by oxidation of hydrazone groups to diazomethylene groups. The diazomethylene polymers prepared above can be further reacted in a variety of ways. of ways. In examples as numbered, diazomethylene-substituted styrene/divinyl benzene copolymer is reacted with (21) N-acetyl glyeine, the product being then nitrosated with nitrosyl chloride, and then treated with BaO to produce polymer-bound diazoacetic acid; (22) allyl alcohol; (23) thiophenol; (24) 2-aminoethanethiol hydrochloride; and (25) methyl-3#- hydroxy-11-oxo-5α-bisnoreholanate. (Note.-The intermediate polymers containing hydrazone groups are the subject of Specification 1,482,923).
Application Number:
JP8793274A
Publication Date:
June 13, 1975
Filing Date:
July 30, 1974
Export Citation:
International Classes:
C08F8/06; C08F8/10; C08F8/30; C08G85/00; C08F8/00; (IPC1-7): C08F8/00; C08F8/06; C08F8/10; C08F8/12; C08F8/14; C08F8/20; C08F8/30; C08F8/34; C08G61/02; C08G85/00