Document Type and Number:
Japanese Patent JPS51110551
Kind Code:
A
Abstract:
Novel retinoic acid esters of anti-inflammatory steroids of the pregnane series are described and their use in the treatment and control of acne vulgaris via the topical or intralesional route. A preferred mode of the invention comprises treating acne by applying topically to the affected area hydrocortisone 21-all-trans-retinoate in concentrations of from about 0.05 to about 0.15 percent. Pharmaceutical formulations and methods for the manufacture of the novel steroidal retinoates are also described.
Inventors:
CHAARUSU JETSUSHI KASUMAA
RICHAADO UIRIAMU DORATSUPAA
RICHAADO UIRIAMU DORATSUPAA
Application Number:
JP1982976A
Publication Date:
September 30, 1976
Filing Date:
February 25, 1976
Export Citation:
Assignee:
SCHERICO LTD
International Classes:
A61K8/04; C07J5/00; A61K8/63; C07J7/00; C07J41/00; C07J71/00; (IPC1-7): A61K31/57; C07J5/00
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