Document Type and Number:
Japanese Patent JPS5320515
Kind Code:
B1
Abstract:
Fatty acid esters of 8-substituted 10-[4-(hydroxyalkyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepins and oxepins having the formula IN WHICH X is a sulfur or oxygen atom, R1 is a hydrogen, chloro, or trifluoromethyl radical, a lower alkyl radical having at most 5 carbon atoms, or a cycloalkyl radical having at least 3 and at most 8 carbon atoms, or an alkoxy or alkylthio radical the alkyl moiety of which has at most 4 carbon atoms, R2 is an alkyl radical having at least 5 and at most 17 carbon atoms, and n is 2, 3, or 4, and their salts with pharmaceutically acceptable inorganic and organic acids. The compounds have a high degree of neuroleptic activity and retain this activity for long periods after administration.
Application Number:
JP5709971A
Publication Date:
June 27, 1978
Filing Date:
July 29, 1971
Export Citation:
International Classes:
C07D313/12; C07D337/14; (IPC1-7): C07D493/04; C07D295/08; C07D313/14; C07D337/14; C07D495/04; C07D497/04