Document Type and Number:
Japanese Patent JPS5324422
Kind Code:
B1
Abstract:
Procedure for obtaining thiourea derivatives, of general formula: **(See formula)** wherein A is such that, together with the carbon atom shown, it forms an unsaturated heterocyclic nucleus comprising at least one nitrogen atom and may further comprise heteroatoms such as sulfur and oxygen; X1 and X2 which may be the same or different, are hydrogen, lower alkyl, trifluoromethyl, hydroxyl, benzyl, halogen, amino (see formula) or X1 can form, with X2 and at least two of the atoms comprising A, an additional ring; 1 and m are integers from zero to 4, provided that the sum of 1 and m is 3 or 4; Y is oxygen, sulfur, or NH; E is oxygen or sulfur; y is hydrogen, lower alkyl, acyl, or dialkylamino-alkyl; characterized in that a compound of formula: **(See formula)** wherein A, X1, X2, 1, m and Y are defined as above, reacted with a compound of formula: R1-N = C = E where R1 and E are defined as above. (Machine-translation by Google Translate, not legally binding)
Application Number:
JP2437172A
Publication Date:
July 20, 1978
Filing Date:
March 09, 1972
Export Citation:
International Classes:
A61K31/415; A61P43/00; C07D213/32; C07D213/65; C07D213/70; C07D213/74; C07D231/12; C07D233/68; C07D233/84; C07D235/06; C07D233/64; C07D249/08; C07D249/12; C07D263/46; C07D277/26; C07D277/36; C07D285/135; C07D295/13; C07D471/04; C07D285/12; (IPC1-7): C07D275/02; C07D213/02; C07D233/54; C07D263/30; C07D277/20; C07D285/12