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Document Type and Number:
Japanese Patent JPS5412464
Kind Code:
B2
Abstract:
5 alpha , 17B-Diacetoxy-6 -chloro-2 alpha , 3 alpha ; 16 alpha , 17 alpha -diepoxy-androstane; 5 alpha , 17B-Dicetoxy-6 -chloro-androsta-2,16-diene; 5 alpha -Hydroxy-6 -chloro-17-oxo-androst-2-ene or a like intermediate in the production of curare-like compounds is produced by reacting 5 alpha , 6B-dihydroxy-17-oxo-androst-2-ene with an organic sulfonic acid chloride. The obtained 5 alpha - hydroxy-6B-chloro-17-oxo-androst-2-ene can then be reacted with the enol acetate of a ketone having 3 to 5 carbon atoms to yield 5 alpha , 17B-diacetoxy-6B-chloro-androsta-2,16-diene. The latter is treated to yield the corresponding diepoxide.

Application Number:
JP8391476A
Publication Date:
May 23, 1979
Filing Date:
July 14, 1976
Export Citation:
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International Classes:
A61K31/565; A61P21/02; C07J1/00; C07J11/00; C07J13/00; C07J31/00; C07J41/00; C07J71/00



 
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