Title:
【発明の名称】動物の細菌感染を阻止するために用いられる薬剤
Document Type and Number:
Japanese Patent JPS58500566
Kind Code:
A
Abstract:
A method for arresting fulminating infections of traumatized animal tissue comprises administering to the locus of the tissue trauma an agent capable of binding iron made available to infection-promoting organisms by body fluid released by the trauma. The agent is administered in an amount sufficient to bind all of the available iron, to thereby block the adsorption of the iron by the infection-promoting organisms. The agent preferably comprises one or more binding proteins having known specificity for iron-containing fractions of the body fluid. In particular, the protein haptoglobin may be utilized in the agent to complex with the hemoglobin fraction of blood, to deny access to the iron content by bacterial enzymes. The present method is preferably used in conjunction with existing infection-controlling therapy.
Inventors:
Cerami Anthony-
Application Number:
JP50176682A
Publication Date:
April 14, 1983
Filing Date:
May 03, 1982
Export Citation:
Assignee:
Ebreka Parakeet-Politeted
International Classes:
A61F13/15; A01N59/00; A61F13/00; A61F13/20; A61F13/472; A61K31/70; A61K31/715; A61K31/74; A61K31/745; A61K31/80; A61K33/00; A61K38/00; A61K38/16; A61K38/17; A61K38/40; A61L15/44; A61L15/46; A61P31/04; (IPC1-7): A61K37/02; A61K31/74; A61K31/70
Other References:
IMMUNOLOGY=1968
IMMUNOLOGY=1971
INFECFON AND IMMUNIFY=1979
IMMUNOLOGY=1971
INFECFON AND IMMUNIFY=1979
Attorney, Agent or Firm:
Maruyama Toshiyuki