Document Type and Number:
Japanese Patent JPS6225656
Kind Code:
B2
Abstract:
The present invention provides a pharmaceutical composition for treating ulcerative colitis containing at least one compound of the general formula: (I) wherein X is an -SO2- or -CO- group and R is either an unsubstituted or substituted non-heterocyclic aromatic ring system or is a radical of the general formula -(CH2)n-Y, in which Y is a hydroxyl group, an unsubstituted or substituted amino group or a carboxylic or sulphonic acid group and n is a whole number of from 1 to 6 and in which one or more hydrogen atoms in the alkylene radical can be replaced by unsubstituted or substituted amino groups or alkyl radicals and in which the -(CH2)n-Y radical is either attached directly to the nitrogen atom or via a benzene ring; and/or containing at least one ester thereof and/or at least one non-toxic, pharmaceutically acceptable salt thereof, in admixture with a solid or liquid pharmaceutical diluent or carrier. Furthermore, the present invention provides a process for preparing the compounds of the above-given general formulae and also provides a method of treating ulcerative colitis.
Inventors:
ROZARINDO BOO KUEN CHAN
Application Number:
JP11153481A
Publication Date:
June 04, 1987
Filing Date:
July 16, 1981
Export Citation:
Assignee:
BIOREX LABORATORIES LTD
International Classes:
A61K31/16; A61K31/60; A61K31/655; A61P1/04; C07C67/00; C07C241/00; C07C245/08; C07C301/00; C07C303/22; C07C303/30; C07C309/15; C07C311/39; C09B29/14