Japanese Patent JPS6230200

B2

Novel steroids of the formula I wherein R1 is selected from the group consisting of hydrogen and acyl of an organic carboxylic acid of 1 to 18 carbon atoms, R2 is selected from the group consisting of optionally substituted aryl of 6 to 12 carbon atoms and optionally substituted heterocyclic selected from the group consisting of furyl, thienyl, pyridyl and pyrimidyl, the optional substituents being selected from the group consisting of hydroxy, alkyl and alkoxy of 1 to 4 carbon atoms, halogens and -CF3, the dotted line in the A ring indicates an optional DELTA 1(2)- double bond and A may be oxo and B is hydrogen or A is DELTA -OH and B is hydrogen or halogen or A and B form a DELTA 9(10)- double bond having very good anti-inflammatory activity and their preparation and novel intermediates.

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ANDORE PIERUDE
BESUPERUTO TORERI
ROJE DORAE

JP105879A

July 01, 1987

January 11, 1979

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ROUSSEL UCLAF

A61K31/565; A61K31/58; A61P29/00; C07J1/00; C07J17/00; C07J33/00; C07J43/00; C07J71/00

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