Japanese Patent JPS633879

B2

Amino-3-cardenolide derivatives represented by the general formula (I) (I) wherein n and m, which may be the same or different, each represents an integer from 0 to 4; R1, R2, R4, R5 and R6, which may be the same or different, each represents a hydrogen atom or a hydroxy, alkoxy or acyloxy group; R3 represents a lower alkyl, aldehyde, haloalkyl, hydroxyalkyl, acyloxyalkyl, or ethylenedioxyalkyl group; R7 represents a hydrogen atom or an alkyl group; R8 represents a hydrogen atom or an alkyl, acyl, alkyloxycarbonyl or aralkoxycarbonyl group; R9 represents a hydrogen atom or an alkyl group; R8 and R9 can combine and form with the nitrogen atom a heterocyclic ring; R10 represents a hydroxy, alkoxy or aralkoxy group, an amino residue of amino acid or of an oligo-peptide, useful especially for the treatment of cardiac ailments.

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FURANSOWA ZAUIERU JAROO
JAN JAKU KEENIJI

JP812579A

January 26, 1988

January 26, 1979

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NATIVELLE SA ETS

A61K31/585; A61P9/04; C07J41/00; C07J43/00

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