【発明の名称】レクチン複合体及びそれを製造する方法及びプローブ - Dana Faber Cancer Institute, Incorporated

Title:

【発明の名称】レクチン複合体及びそれを製造する方法及びプローブ

Document Type and Number:

Japanese Patent JPS63503224

Kind Code:

A

Abstract:

A cytotoxic lectin complex having diminished non-specific toxicity comprising a cytotoxic lectin covalently bonded to a specific ligand comprising a disaccharide or higher polysaccharide derivative capable of binding specifically to an oligosaccharide-binding site on the lectin and a monoclonal antibody covalently bonded to the cytotoxic lectin complex.

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Inventors:

Morrowney, Simon E.
Brettler, Walter A.
Lambert, John M.
Dalarkao, Linda Jay.

Application Number:

JP50218587A

Publication Date:

November 24, 1988

Filing Date:

March 18, 1987

Export Citation:

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Assignee:

Dana Faber Cancer Institute, Incorporated

International Classes:

A61K38/00; A61K38/36; A61K39/00; A61K39/395; A61K47/48; A61P35/00; C07H15/04; C07H15/18; C07H21/00; C07K14/00; C07K14/42; G01N33/53; C07K16/00; C07K17/08; C07K17/14; C07K19/00; C08L5/00; G01N33/543; G01N33/577; (IPC1-7): A61K37/46; A61K39/395; C07K3/20; C07K15/12; C07K15/14; C07K17/08; C07K17/14; C08L5/00; G01N33/53; G01N33/543; G01N33/577

Domestic Patent References:

JPS62169800A

1987-07-25

Attorney, Agent or Firm:

Motohiro Kurauchi (1 outside)

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