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Title:
インスリン初期分泌促進剤
Document Type and Number:
Japanese Patent JPWO2005027891
Kind Code:
A1
Abstract:
下記一般式(1)で表されるトリテルペン及び/又は下記一般式(2)で表されるトリテルペンからなるインスリン初期分泌促進剤を提供する。[式中、R1はCOOH基等、R11及びR12はCH2OH基等、X1は水素原子又はOH基、X11、X12、X21及びX22はOH基等をそれぞれ表す。]

Inventors:
Tadashi Matsuyama
Yuu Seino
Mitsuo Fukushima
Toshihiro Miura
Tsuyoshi Fujita
Tetsuo Kaneko
Application Number:
JP2005514108A
Publication Date:
November 15, 2007
Filing Date:
September 22, 2004
Export Citation:
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Assignee:
Youth Techno Corporation Co., Ltd.
International Classes:
A61K31/56; A23K1/16; A61K31/19; A61K31/20; A61K31/215; A61K31/704; A61K36/18; A61P3/04; A61P3/06; A61P3/10; A61P5/50; A61P9/12; C07C61/28
Domestic Patent References:
JP2005027892A2005-02-03
JPH05310587A1993-11-22
JPS55122715A1980-09-20
Foreign References:
US20030165581A12003-09-04
Other References:
JPN6009062350, IVORRA, M.D. et al., "Effect of tormentc acid on insulin secretion in isolated rat islets of Langerhans", Phytotherapy Resaerch, 1989, Vol.3, No.4, p.145−147
JPN6009032980, 池田義雄ら, "「血糖値が気になる人」におけるバナバ抽出エキス投与による有効性および安全性", プラクティス, 20010708, 18巻4号, pp439−445, JP
JPN6009062355, MURAKAMI,C. et al., "Screening of plant constituents for effect on glucose transport activity on Ehrlich ascites tumor ce", Chemical & Pharmaceutical Bulletin, Vol.41, No.12, p.2129−2131
JPN6009062352, SHEU,S.Y. et al., "The hypoglycemic principle of Mesona procumbens and Orthosiphon stamineus", Taiwan Kexue, 1984, Vol.38, No.1, p.26−31
JPN6009062354, YAMAGISHI, T. et al., "The cytotoxic principles of hyptis capitata and the structures of the new triterpenes hyptatic acid−", Phytochemistry, 1988, Vol.27, No.10, pp.3213−3216
Attorney, Agent or Firm:
Yoshiki Hasegawa
Shiro Terasaki
Yoshinori Shimizu