Title:
新規外用剤
Document Type and Number:
Japanese Patent JPWO2009025239
Kind Code:
A1
Abstract:
A compound represented by the formula (I), salt thereof, or hydrate thereof has an excellent anti-pruritic effect and an excellent effect in terms of metabolism. The topical formulation of the present invention has excellent skin absorption properties of the compound represented by the formula (I), salt thereof, or hydrate thereof. Furthermore, the topical formulation of the present invention is excellent in stability because ingredients are hardly bled after long-term storage.
wherein R represents hydroxyl, C 1-6 alkoxy optionally substituted with C 1-6 alkoxy, or amino optionally substituted with C 1-6 alkyl.
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Inventors:
Kimura Chiharu
Sakurai Maho
Sakurai Maho
Application Number:
JP2009529019A
Publication Date:
November 25, 2010
Filing Date:
August 15, 2008
Export Citation:
Assignee:
Eisai R & D Management Co., Ltd.
International Classes:
C07D239/84; A61K9/06; A61K31/517; A61K47/12; A61K47/14; A61K47/34; A61K47/44; A61P17/00; A61P17/04; A61P37/08; A61P43/00
Attorney, Agent or Firm:
Yoshiki Hasegawa
Yoshinori Shimizu
Kimoto
Yoshinori Shimizu
Kimoto
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