Title:
肝疾患治療剤及び肝疾患を治療する方法
Document Type and Number:
Japanese Patent JPWO2017110425
Kind Code:
A1
Abstract:
本発明は、肝疾患の新規治療剤を提供することを目的とする。本発明は、間質細胞由来の微小粒子を含有する、肝疾患治療剤である。上記微小粒子の平均粒子径は、１，０００ｎｍ以下であることが好ましい。また、本発明の肝疾患治療剤は、上記微小粒子を含有又は分泌する能力を有する間質細胞を含むことが好ましい。
Inventors:
Kurata Hayato
Takahiro Ochiya
Takahiro Ochiya
Application Number:
JP2017557840A
Publication Date:
October 11, 2018
Filing Date:
December 02, 2016
Export Citation:
Assignee:
Rohto Pharmaceutical Co., Ltd.
National Cancer Research Center
National Cancer Research Center
International Classes:
A61K35/35; A61K9/127; A61K9/14; A61K38/16; A61K38/20; A61K38/22; A61P1/16; A61P37/06
Domestic Patent References:
| JP2012056913A | 2012-03-22 | |||
| JP2012502934A | 2012-02-02 |
Foreign References:
| CN101890050A | 2010-11-24 |
Other References:
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TAN, C.Y. ET AL.: "Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury mod", STEM CELL RES THER, vol. 5, no. 3, JPN6016050324, 2014, pages 76, XP021195493, ISSN: 0004496636, DOI: 10.1186/scrt465
KO, S.F., ET AL.: "Adipose-Derived Mesenchymal Stem Cell Exosomes Suppress Hepatocellular Carcinoma Growth in a Rat Mod", STEM CELLS INT, JPN6016050325, August 2015 (2015-08-01), pages 853506, ISSN: 0004496637
Attorney, Agent or Firm:
Patent business corporation Tsukuni